Know Everything About Profhilo Before Anyone ElseDr. Bank explains Profhilo in a nutshell: What is it, and who is it for? - 22 Square Clinic

🕒 : Open daily from 11:00 AM to 8:00 PM.

Know Everything About Profhilo Before Anyone ElseDr. Bank explains Profhilo in a nutshell: What is it, and who is it for?

Profhilo is a treatment that helps with skin rejuvenation, similar to a filler, but with the added benefit of stimulating collagen production through a mechanism similar to biostimulators. However, it works through a process called skin bioremodelling, which sets it apart from other products on the market.

In this article, 22 Square Clinic will introduce you to Profhilo, including its components, the collagen-stimulating mechanism, the results after treatment, the types of skin issues it’s most suitable for, how it differs from other products like Sculptra or Juvelook, and other important things you need to know before deciding to get the injection.

What is Profhilo?

Profhilo is a treatment that involves injecting Hyaluronic Acid (HA), which is popular in the beauty industry for restoring youthful skin. Unlike traditional fillers, Profhilo focuses on hydrating the skin and stimulating collagen production in the dermis, resulting in a firmer, smoother, and more naturally plump appearance.

What are the components of Profhilo and how does it work?

Profhilo consists of both high and low molecular weight Hyaluronic Acid (HA), linked together using a special technique called NAHYCO. This results in HA with a high concentration of 64 mg/ml, the highest available in the market. Despite its high concentration, it does not form clumps, spreads easily, and naturally breaks down. The two types of HA work through different mechanisms:

  • High Molecular Weight HA: This helps the skin appear hydrated and enhances moisture retention in the skin layers.
  • Low Molecular Weight HA: This stimulates the production of collagen and elastin through the process of skin bioremodelling, making the skin firmer and more elastic.

The function of Profhilo focuses on directly boosting skin hydration and stimulating long-term skin rejuvenation:

1.Collagen and Elastin Stimulation
Profhilo is injected into the deeper layers of the skin (dermis), stimulating collagen and elastin production. Collagen tightens and firms the skin, while elastin provides elasticity.

2.Increasing Skin Hydration
Hyaluronic Acid is capable of drawing water into the skin, providing hydration and reducing dryness, which is a major cause of wrinkles and sagging.

3.Improving Skin Elasticity
Profhilo enhances skin elasticity by delivering low molecular weight HA that fills and stimulates the creation of new skin structures, leading to firmer and more taut skin.

4.Treating Sagging and Wrinkles
Profhilo is ideal for reducing sagging and wrinkles caused by the loss of collagen and elastin over time, resulting in younger, more resilient skin.

How is Profhilo different from regular HA fillers?

Many people may wonder how Profhilo, which primarily contains Hyaluronic Acid (HA), differs from regular fillers. Let’s take a look at the types of HA commonly used in the market, which can be divided into two main categories:

  1. Cross-linked HA
    This type of HA is chemically cross-linked using special ingredients like BDDE or PEG to create a gel-like consistency, making it resistant to breakdown in the body. Examples of cross-linked HA fillers include facial fillers like Restylane, Juvederm, or skin treatment fillers like Restylane Vital Light and Juvederm Skinvive. These fillers have a low degree of cross-linking, allowing them to spread well in the superficial layers of the skin. While they help restore volume and smooth wrinkles, they do not effectively stimulate long-term collagen production.

  2. Non-Crosslinked HA
    Non-crosslinked HA does not have molecular bonds, allowing the body to break it down easily within 24-48 hours. An example of this type of HA is found in Juvelook, which provides temporary fullness to the face. However, it doesn’t stimulate collagen production long-term unless other substances, such as PDLLA found in Juvelook, are added to the formula.

Key Differences:

  • Cross-linked HA fillers focus on providing volume and contour, lasting longer in the skin, but don’t stimulate collagen production significantly over time.
  • Non-crosslinked HA offers temporary hydration and volume but is not designed for long-term rejuvenation or collagen stimulation.

Profhilo is a type of non-crosslinked HA.

Profhilo can be misleading when discussing the category of HA it belongs to because it is neither a filler for volume restoration or facial contouring, as found in cross-linked HA, nor a type of HA that dissolves quickly and provides only temporary hydration, like non-crosslinked HA.

Profhilo uses a special production technology that allows HA to remain in the body for an extended period without the use of chemical crosslinkers like BDDE. This reduces the risk of vascular occlusion and enhances collagen stimulation more effectively than regular HA. In other words, Profhilo is a non-crosslinked HA that has undergone specialized processing to stimulate collagen production and last longer in the body compared to standard hyaluronic acid.

In summary, Profhilo is a unique HA with advanced technology that stimulates collagen production and remains in the body longer, distinguishing it from traditional fillers for facial contouring or HA designed for temporary hydration.

Expected results from Profhilo.

  1. Firmer and tighter skin: Stimulates collagen and elastin production, enhancing skin firmness and elasticity.
  2. Reduces wrinkles and deep lines: Helps smooth out fine lines, especially around the nasolabial folds and under the eyes.
  3. Increases hydration: Boosts moisture from within, leaving the skin plump and radiant.
  4. Improves skin elasticity: Strengthens the skin, making it more resistant to sagging.
  5. Treats acne scars: Stimulates collagen production, reducing the appearance of acne scars and improving skin texture.
  6. Long-lasting results: Effects last approximately 6 months to 1 year.
  7. Treats certain skin conditions: Addresses issues like dryness, age-related wrinkles, and scars.

When and how should we choose to use Profhilo?

Many people may wonder when and how to choose Profhilo, especially since there are numerous HA-based fillers available in the market, as well as biostimulators like Sculptra or Juvelook that can also stimulate collagen. Allow me to explain in two specific cases.

Case 1: When you have previously used fillers or biostimulators or regularly undergo such treatments.

In this case, it is important to explain that Profhilo belongs to the HA category, making it capable of addressing skin hydration and structural improvements similar to fillers. Additionally, it stimulates collagen and elastin production across all skin layers through the bioremodelling mechanism, resembling biostimulators. However, there are slight differences; for instance, Sculptra primarily targets deep-layer collagen stimulation, while Juvelook focuses solely on superficial collagen stimulation.

Therefore, for individuals who have previously used fillers or biostimulators, Profhilo can serve as a complementary treatment. It enhances the quality of skin texture and structure by filling in the gaps that the other two types of products may not completely address.

Case 2: When you have never used fillers or biostimulators before.

In this case, Profhilo can be considered an excellent starting point for skin rejuvenation and structural enhancement. Upon injection, Profhilo delivers immediate benefits from its high-concentration HA, which spreads evenly and naturally dissolves. The immediate results include lifted, plumped, and hydrated skin. Over time, the low-molecular-weight HA gradually stimulates collagen and elastin production, continuously improving skin cell functions and overall skin health. As a result, you achieve outcomes comparable to using both HA and biostimulators in a single treatment.

Who is Profhilo suitable for?

  • For individuals with sagging, loose skin lacking elasticity but not volume, who want to achieve a youthful, more elastic, smoother appearance or reduce wrinkles and uneven texture. Profhilo enhances skin glow and hydration without altering facial contours.
  • For those who have used Sculptra and are satisfied with its deep-layer structural improvements that add fullness and bounce but want to refine the superficial skin layer, smooth wrinkles, and improve elasticity.
  • For individuals seeking smooth, plump, and hydrated skin from the superficial to deeper layers, even if they have previously used Juvelook.

For those with acne scars, Profhilo can be combined with laser treatments or Juvelook to stimulate skin rejuvenation in different layers. Juvelook is typically used in the subdermal layer, while Profhilo works in the superficial to mid-dermal layers (intradermal), making it ideal for directly addressing acne scars.

Where can Profhilo be injected?

  • Face
  • Forehead and temples
  • Around the neck
  • Acne scars
  • Areas with sagging or lack of hydration

How is Profhilo injected, and how many sessions are needed to see results?

Profhilo is injected in a variety of ways and is a great option for those who are afraid of needles, as only 5 injection points per side are needed. The product naturally spreads across the face, causing minimal discomfort. Additionally, specific areas in the skin layer can be targeted based on the doctor’s assessment.

Typically, 1-2 syringes (1 syringe = 2 cc) are used per session, and two sessions are recommended, spaced 1 month apart, to stimulate collagen production more effectively and continuously.

Profhilo injection protocol.

  • Standard injection: 1 syringe (2 cc per syringe) per session.
  • Inject 2 sessions, spaced 1 month apart, for a total of 2 syringes.
  • For more significant issues or acne scars, a third session may be added, or the amount may be increased to 2 syringes per session to target specific problem areas.

How long does it take to see results after injecting Profhilo?

Typically, results can be seen about 1 month after treatment, with more noticeable improvements occurring around 2 months. The effects of collagen stimulation and skin rejuvenation last approximately 6-12 months, depending on the severity of the skin concerns and individual responses. For acne scars, the results are permanent, but to maintain the effects, Profhilo injections can be repeated every 6 months.

Example of results before and after Profhilo injection.

Side effects of Profhilo.

Profhilo has a low risk of side effects and is generally not severe. Studies involving nearly 40,000 patients have not found serious vascular side effects such as blockage, tissue necrosis, or blindness. Due to the drug’s ability to spread well and break down easily, the chances of blockage are significantly reduced. Other potential side effects include minor needle marks, bumps, or bruising, which typically resolve within 5-7 days. During this period, normal daily activities can be resumed, and no recovery time is necessary.

Why choose to inject Profhilo at 22 Square Clinic?

Because results… and technique are things that 22 Square Clinic always prioritizes. To achieve good results from treatment, the technique used must be considered, along with the specific issues of the patient. Especially when injecting Profhilo to address different concerns, as Profhilo is a new innovation, it is necessary to assess the skin condition, skin structure, and previous treatments the patient has undergone to determine how they can be combined or applied together. 22 Square Clinic is composed of a team of specialized dermatologists and plastic surgeons, allowing patients to trust and rely on the assessment of their issues and the selection of treatment methods that are tailored to each problem accurately and appropriately.

We also have various advanced tools, including the thermage FLX or ultraformer III lifting machines, which can be used in conjunction with Profhilo injections to enhance the lifting effect. Even for acne scar treatment, Profhilo can be combined with picolaser, fibrosis cutting, or microneedling to improve the effectiveness of scar reduction. Therefore, you can be confident that when receiving Profhilo treatment at 22 Square Clinic, you will receive a comprehensive and appropriate evaluation to ensure your concerns are addressed in the best possible way.

Summary.

Profhilo is a new innovation in collagen stimulation developed using high-concentration Hyaluronic Acid with the patented NAHYCO technology, which helps the substance distribute effectively and stimulates collagen production in the skin excellently.

The highlight of Profhilo is its ability to stimulate collagen in all layers of the skin, both superficial and deep, unlike Sculptra, which only works in the deep layers. This helps the skin appear smoother, increases elasticity, and provides better hydration.

It is suitable for those with sagging skin, wrinkles, or lack of skin elasticity, as well as acne scars, especially those who want to improve skin condition without changing facial features or those who wish to enhance the results of Sculptra or Juvelook treatments.

The treatment involves injecting Profhilo 2 times, spaced 1 month apart. The procedure is minimally painful and requires no downtime. Results can be seen within 1-2 months and will last approximately 6-12 months.

Profhilo is the latest innovation in collagen stimulation that was introduced in Thailand in late 2024. It stands out with its high HA content, which doesn’t clump, distributes well, and has skin bioremodelling effects that help stimulate collagen and elastin. Therefore, it is considered a new treatment that addresses skin rejuvenation and conditioning across all layers, reducing sagging, lifting, and effectively treating acne scars. It is recommended to have at least 2 injections spaced 1 month apart for results lasting 6-12 months.

At 22 Square Clinic, we have a team of expert dermatologists ready to provide consultations to ensure your skin health.

“We Care For You Beyond Skin Deep, ให้เราดูแลทุกจัตุรัสบนผิวคุณ”

Share:

Facebook
Twitter
LinkedIn

Table of Contents

Related Posts

social media
Quick Links
Get In Touch

628 Soi Suan Phlu 7 Sathon, Bangkok, Thailand, Bangkok

© 22 Square Clinic

Scroll to Top